Analysts say loss of Toprol XL patent a significant threat to AstraZeneca

Share this article:
AstraZeneca faces a significant risk of losing US patent protection on its top selling heart drug Toprol XL (metoprolol succinate), according to analysts from Deutsche Bank. The analysts estimate there is around a 40 percent chance AstraZeneca will lose a ruling on the drug, according to a report from Reuters today. AstraZeneca has maintained its expectation of exclusivity on Toprol XL to hold until Sept. 2007, when US patents expire. The challenges to Toprol XL patents come from KV Pharmaceutical, Andrx Corp. and Eon Labs, a unit of Novartis. Sales of Toprol XL are expected to total around $1.3 billion in 2005. Generic drug makers have also recently challenged AstraZeneca’s two biggest sellers, the anitulcerant Nexium (esomeprazole magnesium delayed-release capsules), and Seroquel (quetiapine fumarate) for schizophrenia. In November AstraZeneca filed a lawsuit against Ranbaxy Laboratories in an attempt to stop the Indian drug maker from launching a copycat version of its top-selling medicine Nexium. Also in November, AstraZeneca filed a lawsuit against Teva Pharmaceuticals for infringement of AstraZeneca's substance patent protecting Seroquel.
Share this article:
You must be a registered member of MMM to post a comment.

Email Newsletters

More in News

Five things for Pharma Marketers to know: Friday, August 29

Five things for Pharma Marketers to know: Friday, ...

Takeda closes out a good-news, bad-news kind of week, AstraZeneca adds a new clinical trial for its experimental PD-1, and researchers link a funeral to the Ebola outbreak.

Amgen sends PCSK9 to FDA

Amgen sends PCSK9 to FDA

Evolocumab holds the FDA's first filed biologics license application for the class.

Consultants expect M&A tempo to continue

Consultants expect M&A tempo to continue

PwC anticipates that divestitures will fuel late-2014 deals, but notes that the noise around early deals and the financials don't fully match up.