Company news: Abbott, Vertex
Vertex announced Monday that its Phase II results of VX-809 and Kallydeco for treatment of cystic fibrosis showed significant improvement of lung function in patients with two copies of the most common mutations in the gene F508del. Full data is expected by the middle of this year. Today's results were based on patients that reached 56 days of treatment. “Lung function is the single most important marker of disease progression for people with cystic fibrosis, and improvement in lung function is the goal of every new CF therapy,” Michael Boyle, the study's lead investigator and an Associate Professor of Medicine at John's Hopkin's Adult Cystic Fibrosis Center said in a statement. ISI analyst Mark Schoenebaum said in a brief he expects Vertex will slash the cost of the drug regimen from $300,000 to $100,000, and says the combo could hit peak sales of $4 billion a year.