Company news: AstraZeneca, ViiV

Share this article:
Pfizer's pending-approval RA drug tofacitnib already has a contender in the pipeline – AstraZeneca's fostamatinib, which sounds similar, but is an SYK Kinase inhibitor as opposed to JAK inhibitor. Bernstein Analyst Tim Anderson said in his November 15 research note that AstraZeneca hosted a meeting to highlight its Phase III treatment's results, and his takeaway was that the investment community should be cautious. Anderson flagged raised blood pressure among clinical trial patients as a cause of concern, because RA patients are already “at heightened risk of having CV events.” Anderson acknowledged that add-on meds could be used to lower blood pressure, but wrote that may not placate regulators, particularly because the RA category already has treatments that don't have this affect.

ViiV healthcare partners GlaxoSmithKline, Pfizer and Shionogi announced Monday that the experimental HIV drug dolutegravir reduced the virus levels among hard-to-treat patients who were part of the Phase III Viking study. The study showed that the virus was undetectable in 63% of the 183 patients after 24 weeks, reported Bloomberg. These patients were unresponsive to several antivirals. The announcement is soon after GSK traded Shionogi shares in ViiV for ownership of the partnership's HIV therapy portfolio.
Share this article:
close

Next Article in Business Briefs

Email Newsletters

More in Business Briefs

Biologics have higher psoriatic arthritis adherence

A study of psoriatic arthritis patients found greater adherence among patients whose initial treatment was a biologic, compared to those who started with a non-biologic treatment.

IRS struggles with device tax

A Treasury report says the IRS is having trouble identifying who owes it money.

White House proposes Hobby Lobby alternative

A proposal by the Obama administration Friday seeks to keep contraception accessible and coverage approval at arm's length for employees of religious non-profits.