Amgen said on Monday that 2,200 employees would lose their jobs under a company restructuring that includes about 675 layoffs at its headquarters in Thousand Oaks, CA, The Ventura County Star reported.

The total number of job cuts was close to what the company estimated when it announced in August that 2,200 to 2,600 job cuts were needed as part of a plan to reduce costs.  Amgen has seen decreased revenue during 2007 from its main anemia drug, Aranesp, after studies that raised safety concerns about anemia drugs and changes in how Medicare pays for them.