JAMA study links Parkinson's drugs and compulsive behavior

An abstract published in JAMA Internal Medicine Monday suggests a link between a class of drugs known as dopamine receptor agonists—which are used to treat Parkinson's disease, restless leg syndrome and hyperprolactinemia—and pathological gambling, hyper sexuality and compulsive shopping. After identifying 1,580 events indicating impulse-control disorders from the US and 21 other countries, researchers found “the dopamine receptor agonist drugs had a strong signal associated with these impulse control disorders.” Research concluded that their “findings confirm and extend the evidence that dopamine receptor agonist drugs are associated with these specific impulse-control disorders. Our data, and data from prior studies, show the need for more prominent warnings.”