1. Novartis continues to struggle to sell Entresto, its new heart-failure drug, citing reimbursement issues and cardiologists’ prescribing habits. The drug generated $21 million in sales in the six months after its launch, which fell short of the $126 million in sales expected by analysts. (WSJ)

2. GlaxoSmithKline said CEO Andrew Witty would retire next year, an announcement that prompted a top investor in the company to call for an external candidate to replace Witty. (Reuters)

3. A new study published in the Journal of the American Medical Association found that four common technology assistants, including Google’s Now and Apple’s Siri, have gaps in how they respond to health-related requests from women compared to men. Other health tools such as Apple’s HealthKit have also failed to take into account women’s health needs. (Quartz)

4. A ProPublica investigation discovered ties between physicians who receive payments from manufacturers and the volume of brand-name drugs those doctors prescribe. This includes physicians who only took meals from drug and devicemakers. (NPR)

5. Researchers tested a dengue vaccine developed by National Institutes of Health scientists and found it protected all participants in a small study. (Reuters)