1. FDA commissioner Scott Gottlieb said prescription drug manufacturers are “gaming the system” when it comes to generic competition, in order to protect the high prices of brand-name drugs. (USA Today)

2. President Trump’s criticism of Merck and the industry’s drug pricing practices did little to worry investors. The Nasdaq Biotech Index rose by 1%, while Merck inched up half a point on Tuesday. (Endpoints News)

3. Doctors are increasingly supportive of a single-payer health system, more so than they were in 2008, according to a new survey. The primary reason is the administrative hassle associated with billing and paperwork. (Kaiser Health News)

4. The state of South Carolina sued Purdue Pharma, accusing the drugmaker of using deceptive marketing tactics to sell opioids. (WSJ)

5. ICYMI: Goldman Sachs reportedly suggested that Amazon might partner with a PBM to gain entry into the pharmacy market. One challenge is that Amazon’s customer base skews younger — and healthier — than the people who are most likely to take prescription drugs. (CNBC)