GSK, Celgene cough up milestone payments

Share this article:

Epizyme announced Monday that its experimental orphan drug for acute leukemia, EPZ-5676, achieved its proof-of-concept milestone, triggering a $25-million payment from partner Celgene. The drug is for patients in whom the MLL gene is rearranged due to a chromosomal translocation or partial tandem duplication. The conditions result in “an increased expression of genes causing leukemia.”

The Cambridge, MA, company also scored $4 million from partner GlaxoSmithKline for a milestone payment associated with one of three histone methyltrasferase targets. The companies joined up in 2011 for a deal that includes up to $626 million in milestone payments and sales-based milestone payments of up to $270 million.

Share this article:
You must be a registered member of MMM to post a comment.

This compelling e-book shares a wealth of insights designed to help members of sales forces connect with elusive HCPs. An expanded version has also been created that includes video interviews and other multimedia content. Click here for access.