Prevacid follow-up to move into Phase III trials

Share this article:
Japan's Takeda Pharmaceutical said today that a successor to its blockbuster anti-ulcer drug Prevacid would move into Phase III trials in the U.S.
A spokesman for Takeda told Reuters the FDA had allowed the company to skip Phase II clinical trials of the compound, known as TAK-390MR, because its molecular structure is a mirror image of Prevacid.
"Phase I clinical trial data have shown that TAK-390MR may have the potential to bring additional benefits to patients who suffer from acid-related diseases," said Francois-Xavier Frapaise, vice president of research and development for TAP Pharmaceutical Products, the joint venture between Takeda and Abbott Laboratories which, pending approval, would market the compound in the U.S. "We are enthusiastic to initiate a comprehensive Phase III clinical program involving more than 5,000 patients."
Takeda's president Yasuchika Hasegawa first revealed TAK-390MR earlier this month. Hasegawa said in published reports that the company aimed to release the drug in 2008.
Analysts are closely eyeing development of TAK-390MR. The compound's success could help cushion the huge losses expected for Takeda's profits when Prevacid's patent expires in 2009.
Global sales of Prevacid reached $3.4 billion last year – 37 percent of Takeda's total sales
Share this article:

Next Article in Business Briefs

Email Newsletters

More in Business Briefs

Novartis apologizes for slow reporting

Novartis is apologizing to Japan after the Ministry of Health, Labor and Welfare said the company had dragged its feet reporting adverse events for two of its cancer drugs.

J&J pulls morcellator from market

The company is calling the move a withdrawal, as opposed to a recall.

Pfizer buys two Baxter vaccines

The meningitis and encephalitis medications earned a combined $300 million last year.