Prevacid follow-up to move into Phase III trials

Share this article:
Japan's Takeda Pharmaceutical said today that a successor to its blockbuster anti-ulcer drug Prevacid would move into Phase III trials in the U.S.
A spokesman for Takeda told Reuters the FDA had allowed the company to skip Phase II clinical trials of the compound, known as TAK-390MR, because its molecular structure is a mirror image of Prevacid.
"Phase I clinical trial data have shown that TAK-390MR may have the potential to bring additional benefits to patients who suffer from acid-related diseases," said Francois-Xavier Frapaise, vice president of research and development for TAP Pharmaceutical Products, the joint venture between Takeda and Abbott Laboratories which, pending approval, would market the compound in the U.S. "We are enthusiastic to initiate a comprehensive Phase III clinical program involving more than 5,000 patients."
Takeda's president Yasuchika Hasegawa first revealed TAK-390MR earlier this month. Hasegawa said in published reports that the company aimed to release the drug in 2008.
Analysts are closely eyeing development of TAK-390MR. The compound's success could help cushion the huge losses expected for Takeda's profits when Prevacid's patent expires in 2009.
Global sales of Prevacid reached $3.4 billion last year – 37 percent of Takeda's total sales
Share this article:
You must be a registered member of MMM to post a comment.

Next Article in Business Briefs

Email Newsletters


Patient access to pharmaceuticals is a tale of two worlds—affordability has improved for the majority, while the minority is hampered by cost, distribution and red tape. To provide marketers with a well-rounded perspective, MM&M presents this e-book chock full of key insights. Click here to access it.

More in Business Briefs

Novartis said to be stepping out of HCV

Novartis is said to have relinquished rights to an investigational hep. C treatment, signaling its exit from the therapeutic space, according to a former partner's announcement.

Monday Moves: September 15

Hires and promotions for manufacturers, regulatory and agencies

Kantar acquires Evidências, expands Brazilian presence

The company's acquisition signals the growing importance of understanding the Brazilian healthcare market and evidence-based healthcare management services.