Roche’s Spark Therapeutics will spend $575 million to build a gene therapy innovation center in Philadelphia. The plan would double Spark’s physical footprint. (Endpoints News)

Therapists are seeing high patient demand amid a growing mental health crisis, a new survey found. Nine out of 10 therapists say the numbers of patients seeking care is rising, and therapists are experiencing burnout as well as having to turn patients away. (The New York Times)

The Biden administration hopes to spur antibiotic development among drugmakers as concerns over antibiotic resistance simmer in the background of COVID-19. If implemented, the Pasteur Act would incentivize drug makers to invest in antibiotics. (STAT)

Holiday gatherings with vaccinated family members and friends should still be fairly low-risk even as Omicron spreads, Dr. Anthony Fauci said. He noted, however, that “a lot of breakthrough infections” are occurring and the risk is never zero. (CNBC Weekly)

A federal judge overturned the $4.5 billion settlement between Purdue Pharma and the Sackler family. The ruling will be appealed. (The Wall Street Journal)