Angry at Vertex Pharmaceuticals’ pricing of cystic fibrosis drugs, families in four countries have petitioned to override patents. The effort comes as Vertex released its year-end earnings report Tuesday morning. (STAT News)

Have an inside look at the Senate’s bipartisan drug pricing push. A bipartisan group of senators has been pushing a bill for years to crack down on what they say is patent abuse by drug companies. (Axios)

New York City will end its COVID-19 vaccine mandate for city employees on Friday, Mayor Eric Adams announced this week. Adams noted that most city employees, around 96%, have been fully vaccinated. (ABC News)

TILT Biotherapeutics raised about $23 million in a second round of funding for its cancer therapy pipeline. The new funding will go toward TILT’s lead candidate, TILT-123, an oncolytic virus therapy that’s currently in Phase I trials for solid tumors, melanoma, ovarian cancer and lung cancer. (Endpoints News)

A technology columnist argued that Philadelphia is not the underdog for life sciences startups — or the Super Bowl. “In reality, however, Philly and its environs actually constitute one of the larger U.S. hubs for health and biotech founders,” Joanna Glasner wrote. (Crunchbase News)