Matthew McConaughey is here to talk about life’s moments.

As part of a public service announcement (PSA) released Wednesday morning, the Academy Award-winning actor is highlighting the work of Stand Up To Cancer (SU2C) in raising money to fund cancer research.

The spot, which was released by SU2C and Visit Myrtle Beach, features McConaughey talking about the joys and memories that constitute so many life moments while also noting that a cancer diagnosis can significantly impact those moments, too. 

Following the story of a family that frequently visits the beach, McConaughey narrates how SU2C continually raises money in order to boost support for improved cancer prevention, early diagnoses and more effective treatments. 

The minute-long spot was directed by Brian Morrow and produced by video production studio Sharkpig. The PSA will be placed across a series of channels, including print, broadcast, radio, digital and out-of-home outlets.

McConaughey has supported SU2C since 2014 by participating in various awareness initiatives, including the organization’s biennial TV fundraisers.

“It’s helpful to know that organizations like SU2C exist and can help people find the best information and doctors available,” McConaughey said in a statement. “This PSA highlights the magical moments in life but also points out that there are hard moments as well. The work that SU2C does is groundbreaking and vital to helping get people to more of those magical moments and I am honored to be working with them on this campaign.”

Cofounded in 2008, SU2C has never lacked for involving celebrities and prominent figures in its marketing efforts to support cancer research.

Earlier this year, the organization released a PSA featuring five researchers and scientific leaders supported by SU2C’s funding as they discuss how the donations have allowed them to provide better care to their patients. 

The PSA originally aired in a longer format during the 2021 SU2C telecast but is now being supported by an extended broadcast push. For the next 12 months, 30- and 15-second versions will run via donated media across national and regional broadcast networks as well as out-of-home networks and digital platforms.

Additionally, SU2C celebrated its 15-year anniversary over the summer at its biennial event that was hosted on the four major U.S. broadcast networks in addition to several other media platforms. 

The show featured appearances from celebs like Justin Timberlake, Melissa McCarthy and performances by The Who, among others.