Purdue Pharma has offered $10 billion to $12 billion to settle opioid lawsuits. The proposed settlement would resolve more than 2,000 combined lawsuits that claim Purdue and its owners, the Sackler family, are partially responsible for the opioid crisis. (NBC News)

Newly unsealed video showed Richard Sackler discussing Oxycodone marketing. Sackler, who served as president and co-chairman of Purdue’s board, defended the company’s marketing tactics in a deposition in a Kentucky lawsuit that Purdue had settled. (STAT)

North Carolina has sued eight vaping companies for targeting children. The lawsuit claims that the vape companies used flavors, marketing strategies and inadequate age-verification systems to sell to teens. North Carolina has also filed a similar lawsuit against Juul. (CNBC)

AstraZeneca’s Farxiga has been fast-tracked by the Food and Drug Administration. The drug, which has been approved to treat type 2 diabetes, is being tested to prevent heart and kidney failure in patients with chronic kidney disease. (Reuters)

A former top staffer at the Food and Drug Administration is joining Regeneron. Dr. Edward Cox, former director of the Office of Antimicrobial Products, will serve as regulatory VP at the biotechnology company. (Endpoints)