Company news: AstraZeneca

Share this article:
AstraZeneca experimental blood thinner Brilinta (ticagrelor) got a recommendation from an FDA advisory panel Wednesday. AZ is seeking approval of the drug for reducing thrombotic events in patients with acute coronary syndromes, or heart attacks. One issue, though, caused debate among panelists: North American patients fared better on market leading Plavix than on Brilinta. These geographic differences could pose a commercial hurdle, said Bernstein analyst Tim Anderson. “Competitors Bristol-Myers Squibb/Sanofi-Aventis (who sell Plavix) and Eli Lilly/Daiichi Sankyo (who sell Effient) will very likely have marketing materials calling attention to that section of the Brilinta label describing the unfavorable US findings,” Anderson wrote in a research note. “They will also likely point out other attributes such as Brilinta's twice-daily dosing (versus their once-daily dosing) and side effects such as ventricular pauses and dyspnea (shortness of breath).” Payers may also limit Brilinta uptake once Plavix goes generic in 2012, Anderson pointed out.
Share this article:
close

Next Article in Business Briefs

Email Newsletters

More in Business Briefs

Social media perceived as clinical trial risk

The Wall Street Journal reports that patients are sharing a plethora of information about their clinical trial experiences, from how to get picked, to how to figure out who is in a control group.

Cancer PSA features scientists

Stand Up To Cancer is kicking off a PSA that features Grammy-winner Jennifer Hudson and a Genentech scientist.

Lawmakers eye pricing

The Senate Judiciary Committee's antitrust panel is looking into how three major pharmaceutical manufacturers decided to set minimum prices for their contact lenses.