IBM is requiring its U.S. employees to be fully vaccinated by December 8 or risk unpaid suspension. It becomes the latest company to implement strict vaccine mandates in line with President Biden’s mandate for government contractors. (CNBC Weekly)

Results from Sanofi’s first study on a high-dose flu vaccine paired with a COVID-19 mRNA booster were encouraging, the company announced. “These positive results could facilitate… influenza and COVID-19 booster vaccination campaigns,” Sanofi’s Dr. Michael Greenberg said. (Reuters)

President Biden will soon appoint a permanent Food and Drug Administration commissioner, but it’s unclear who will fill the role. Top candidate Laurie Glimcher, CEO of the Dana-Farber Cancer Institute, removed herself from the running. (Endpoints News)

A combination of Amgen’s KRAS-blocking cancer drug, Lumakras, and other medicines did not improve tumor responses, trial results showed. The company has been testing Lumakras combo therapies to see if they lead to increased efficacy. (STAT)

Tension between the federal government and Moderna is growing after the White House pressured the vaccine maker to boost international donations of its shots in 2022. Moderna has resisted the pressure, citing concerns about balancing domestic and international responsibilities. (Politico)