The Senate failed to codify abortion protections in a vote on Wednesday. Senate Majority Leader Chuck Schumer held a vote on the Women’s Health Protection Act just over a week after a leaked draft opinion indicated the Supreme Court would soon strike down Roe v. Wade. (USA Today)

Takeda posted a full-year profit decline of 9.5%, but said it expects to rebound. The company’s chief executive Christophe Weber estimated that core operating profit will likely exceed 1 trillion yen this fiscal year. (Reuters)

Inovio Pharmaceuticals has replaced its longtime CEO and discontinued work on a COVID-19 vaccine. Jacqueline Shea, the company’s chief operating officer since March 2019, will take over for J. Joseph Kim. (Philadelphia Business Journal

Health experts warned that failing to address a global surplus of COVID vaccines increases the risk of new variants emerging. “We need to invest now because we’re going to continue to see more transmissible variants,” said Thomas Bollyky, director of the global health program at the Council on Foreign Relations. (Fortune)

Five biotech stocks are set to outpace Q1 earnings estimates. Angion Biomedica, Applied Therapeutics, Bolt Biotherapeutics, Ikena Oncology and Landos Biopharma are expected to deliver a beat in their upcoming quarterly reports. (Nasdaq)